Table 2.
Partial correlation analyses for the associations between TMAO-related metabolites and lipids before rosuvastatin therapy (n = 112)
Variables | TMAO | Choline | Carnitine | Betaine | GBB | |||||
---|---|---|---|---|---|---|---|---|---|---|
r | P | r | P | r | P | r | P | r | P | |
TG | 0.294 | 0.002 | −0.020 | 0.839 | −0.046 | 0.632 | −0.008 | 0.936 | −0.135 | 0.161 |
TC | 0.156 | 0.106 | 0.093 | 0.338 | 0.073 | 0.451 | −0.093 | 0.334 | 0.075 | 0.439 |
HDL-c | −0.316 | 0.001 | −0.098 | 0.313 | −0.009 | 0.923 | −0.105 | 0.275 | 0.003 | 0.977 |
LDL-c | 0.040 | 0.680 | −0.037 | 0.702 | −0.090 | 0.351 | −0.269 | 0.005 | 0.043 | 0.654 |
ApoA1 | −0.081 | 0.404 | −0.075 | 0.441 | 0.070 | 0.468 | −0.086 | 0.373 | −0.035 | 0.715 |
ApoB | 0.021 | 0.828 | 0.096 | 0.320 | 0.042 | 0.668 | −0.028 | 0.772 | 0.076 | 0.429 |
TMAO Trimethylamine N-oxide, TG Triglycerides, TC Total cholesterol, HDL-c High-density lipoprotein cholesterol, LDL-c Low-density lipoprotein cholesterol, ApoA1 Apolipoprotein A1, ApoB Apolipoprotein B, GBB γ-butyrobetaine. Partial correlation was performed by controlling for sex, age, body mass index and estimated glomerular filtration rate.