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. 2015 Jun 18;2015(6):CD010856. doi: 10.1002/14651858.CD010856.pub2

Wenzel 1982.

Methods FLUOROSIS STUDY
Country of study: Denmark
Geographic location: Naestved (F); Greve (F); Ry (non‐F)
Year of study: not stated
Year of change in fluoridation status: not stated
Study design: cross‐sectional
Participants Inclusion criteria: lifetime residents of study areas; girls aged 12‐15 years
Exclusion criteria: children with orthodontic appliances; history of additional fluoride use
Other sources of fluoride: only children without fluoride use were included; no attempt was made to distinguish between users and non‐users of fluoridated dentifrice
Social class: not stated
Ethnicity: not stated
Residential history: lifetime residents
Other confounding factors: not stated
Interventions Group 1: < 0.2 ppm
Group 2: 1.0 ppm
Group 3: 2.4 ppm
Outcomes Fluorosis (TF Index); skeletal maturity
Age at assessment: 12‐14 years
Funding Sponsored by Colgate Palmolive, Denmark
Notes Data extracted Wenzel 1982 differs from that presented in CRD review
Risk of bias
Bias Authors' judgement Support for judgement
Sampling Unclear risk Insufficient detail reported to determine how selection took place
Confounding High risk Did not account for SES
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Insufficient information
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Data for all participants presented
Selective reporting (reporting bias) Low risk Outcome of interest presented
Other bias High risk No information on examiner calibration
HHS Vulnerability Disclosure