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. 2015 Jun 18;2015(6):CD010856. doi: 10.1002/14651858.CD010856.pub2

Selwitz 1995.

Methods FLUOROSIS STUDY
Country of study: USA
Geographic location: Kewanee (optimal), Monmouth (2 x optimal), Abingdon, Elmwood (3 x optimal), Bushneell, Ipava, Table Grove (4 x optimal), Illinois
Year of study: 1980
Year study ended: 1990
Year of change in fluoridation status: unclear
Study design: repeated cross‐sectional
Participants Inclusion criteria: children aged 8‐10 years and 14‐16 years; written parental consent; lifetime residents of study areas; continuous use of community water supply
Exclusion criteria: none stated
Other sources of fluoride: not stated
Social class: not stated
Ethnicity: not stated
Residential history: lifetime residents
Other confounding factors: not stated
Interventions Unclear whether all was natural fluoridation, parts of the optimally fluoridated area may have been artificially adjusted
Group 1: 4 ppm
Group 2: 3 ppm
Group 3: 2 ppm
Group 4: 1 ppm
Outcomes Dental fluorosis (% fluorosed surfaces (TSIF); caries data also evaluated within the study but excluded from review due to study design
Age at assessment: 8‐10 years and 13‐15 years
Funding Not stated
Notes Data extracted from Selwitz 1995 differs from that presented in CRD review
Risk of bias
Bias Authors' judgement Support for judgement
Sampling Unclear risk There was insufficient detail reported to determine how selection took place. Reference was made to a previous study (Leverett 1986) for further information on sampling, however this study also reported insufficient information on sampling
Confounding High risk Did not account for the use of fluoride from other sources or SES
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Insufficient information
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Data presented for all participants
Selective reporting (reporting bias) High risk Data not in suitable format for analysis
Other bias Low risk No other apparent bias