Table 1.
Participant characteristics overall and by race, N=322.
| ARIC Visit 1 (1987-1989) | ARIC Visit 5 (2011-2013) | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Overall (N=322) |
Blacks (n=139) |
Whites (n=183) |
Overall (N=322) |
Blacks (n=139) |
Whites (n=183) |
|
| Age (years), mean (SD) | 52.2 (5.2) | 52.0 (5.1) | 52.4 (5.3) | 75.8 (5.3) | 75.6 (5.2) | 76.0 (5.5) |
| Female, No. (%) | 185 (57.5) | 85 (61.2) | 100 (54.6) | 185 (57.5) | 85 (61.2) | 100 (54.6) |
| Education level, No. (%) | ||||||
| College, graduate, or professional school | 132 (41.0) | 60 (43.2) | 72 (39.3) | 132 (41.0) | 60 (43.2) | 72 (39.3) |
| High school, GED, or vocational school | 139 (43.2) | 50 (36.0) | 89 (48.6) | 139 (43.2) | 50 (36.0) | 89 (48.6) |
| < High school | 51 (15.8) | 29 (20.9) | 22 (12.0) | 51 (15.8) | 29 (20.9) | 22 (12.0) |
| APOE ε4 genotype, No. (%) | ||||||
| 2/2 or 2/3 or 3/3 | 222 (68.9) | 88 (63.3) | 134 (73.2) | 222 (68.9) | 88 (63.3) | 134 (73.2) |
| 2/4 or 3/4 | 92 (28.6) | 46 (33.1) | 46 (25.1) | 92 (28.6) | 46 (33.1) | 46 (25.1) |
| 4/4 | 8 (2.5) | 5 (3.6) | 3 (1.6) | 8 (2.5) | 5 (3.6) | 3 (1.6) |
| Body mass index (kg/m2), mean (SD) | 27.4 (4.4) | 28.4 (4.5) | 26.7 (4.1) | 29.0 (5.3) | 29.8 (5.3) | 28.4 (5.1) |
| Body mass index ≥30 kg/m2, No (%) | 83 (25.8) | 45 (32.4) | 38 (20.8) | 121 (37.6) | 62 (44.6) | 59 (32.2) |
| Current Smoking, No. (%) | 55 (17.1) | 24 (17.3) | 31 (16.9) | 16 (5.0) | 8 (5.8) | 8 (4.4) |
| Hypertension, No. (%) | 95 (29.5) | 58 (41.7) | 37 (20.2) | 230 (71.4) | 114 (82.0) | 116 (63.4) |
| Diabetes, No. (%) | 20 (6.2) | 7 (5.0) | 13 (7.1) | 130 (40.4) | 55 (39.6) | 75 (41.0) |
| Total cholesterol (mg/dl), mean (SD) | 208.3 (39.0) | 211.3 (41.9) | 206.0 (36.6) | 180.8 (39.6) | 185.1 (42.2) | 177.5 (37.4) |
| Total cholesterol ≥200 mg/dl, No. (%) | 180 (55.9) | 79 (56.8) | 101 (55.2) | 94 (29.2) | 47 (33.8) | 47 (25.7) |
| 10-year stroke risk score* (%), median (IQR) | 1.0 (0.6, 1.7) | 1.4 (0.8, 2.4) | 0.8 (0.5, 1.3) | 11.9 (5.3, 22.6) | 14.0 (7.2, 27.4) | 8.6 (4.0, 17.9) |
| Number of vascular risk factors**, No. (%) | ||||||
| 0 vascular risk factors | 65 (20.2) | 22 (15.8) | 43 (23.5) | 35 (10.9) | 6 (4.3) | 29 (15.9) |
| 1 vascular risk factor | 123 (38.2) | 46 (33.1) | 77 (42.1) | 82 (25.5) | 30 (21.6) | 52 (28.4) |
| 2 vascular risk factors | 93 (28.9) | 46 (33.1) | 47 (25.7) | 116 (36.0) | 57 (41.0) | 59 (32.2) |
| 3 vascular risk factors | 40 (12.4) | 25 (18.0) | 15 (8.2) | 79 (24.5) | 42 (30.2) | 37 (20.2) |
| 4 vascular risk factors | 1 (0.3) | 0 (0.0) | 1 (0.6) | 10 (3.1) | 4 (2.9) | 6 (3.3) |
| 5 vascular risk factors | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Mild cognitive impairment, No. (%) | – | – | – | 87 (27.0) | 37 (26.6) | 48 (27.3) |
*
10-year stroke risk score visit 1 N=305 (n=134 blacks and n=171 whites) with non-missing data. 10-year stroke risk score visit 5 N=304 (n=131 blacks and n=173 whites) with non-missing data. 10-year stroke risk score includes race, smoking status, age, prior coronary heart disease, antihypertensive medication use, left ventricular hypertrophy, diabetes status, systolic blood pressure, and sex.20
**
Vascular risk factors included: body mass index ≥30 kg/m2, current smoking, hypertension, diabetes, and total cholesterol ≥200 mg/dl.