Table 3.

Association of major dietary protein sources (in quintiles) with stroke incidence, ARIC 1987 – 2011

	Q 1	Q 2	Q 3	Q 4	Q 5	p-trend
Processed Meat
n	2333	2731	1838	2427	2272
Events, n	122	156	116	119	186
Median svg/day	0	0.14	0.35	0.50	1.07
HR (95%CI)^*	1 (ref)	1.18 (0.92, 1.51)	1.12 (0.86, 1.45)	1.02 (0.79, 1.32)	1.54 (1.20, 1.98)	0.0002
HR (95%CI)^**	1 (ref)	1.06 (0.83, 1.36)	1.02 (0.78, 1.34)	0.86 (0.66, 1.13)	1.24 (0.94, 1.63)	0.04
Red Meat
n	2510	2115	2506	2212	2258
Events, n	130	107	161	154	147
Median svg/day	0.14	0.28	0.50	0.65	1.08
HR (95%CI)^*	1 (ref)	1.15 (0.89, 1.48)	1.43 (1.12, 1.82)	1.51 (1.18, 1.94)	1.65 (1.26, 2.15)	<0.0001
HR (95%CI)^**	1 (ref)	1.13 (0.87, 1.47)	1.37 (1.06, 1.77)	1.38 (1.05, 1.81)	1.41 (1.04, 1.92)	0.01
Red Meat & Processed Meat
n	2379	2290	2314	2289	2329
Events, n	106	126	157	139	171
Median svg/day	0.25	0.54	0.85	1.21	1.90
HR (95%CI)^*	1 (ref)	1.27 (0.98, 1.64)	1.58 (1.23, 2.04)	1.38 (1.06, 1.81)	1.78 (1.35, 2.35)	<0.0001
HR (95%CI)^**	1 (ref)	1.15 (0.88, 1.51)	1.39 (1.06, 1.81)	1.13 (0.84, 1.52)	1.38 (1.00, 1.91)	0.06
Poultry
n	1663	3163	1344	3176	2255
Events, n	111	185	76	208	119
Median svg/day	0.07	0.14	0.28	0.43	0.80
HR (95%CI)^*	1 (ref)	0.92 (0.73, 1.17)	0.73 (0.55, 0.97)	0.87 (0.68, 1.11)	0.78 (0.60, 1.01)	0.12
HR (95%CI)^**	1 (ref)	0.90 (0.71, 1.15)	0.87 (0.65, 1.15)	0.90 (0.70, 1.16)	0.86 (0.65, 1.14)	0.55
Dairy
n	2367	2299	2326	2259	2350
Events, n	162	154	122	135	126
Median svg/day	0.14	0.57	1.07	1.50	2.86
HR (95%CI)^*	1 (ref)	1.02 (0.82, 1.28)	0.73 (0.57, 0.93)	0.85 (0.67, 1.08)	0.79 (0.61, 1.03)	0.04
HR (95%CI)^**	1 (ref)	1.12 (0.89, 1.40)	0.78 (0.61, 1.00)	0.93 (0.73, 1.20)	0.86 (0.65, 1.15)	0.15
High-Fat Dairy
n	2298	2335	2547	2173	2248
Events, n	136	129	165	137	132
Median svg/day	0.07	0.14	0.43	0.80	1.23
HR (95%CI)^*	1 (ref)	1.02 (0.80, 1.29)	1.17 (0.93, 1.49)	1.02 (0.80, 1.31)	0.99 (0.77, 1.28)	0.85
HR (95%CI)^**	1 (ref)	1.05 (0.82, 1.33)	1.17 (0.92, 1.49)	1.06 (0.82, 1.36)	0.92 (0.71, 1.20)	0.37
Low-Fat Dairy
n	3130	1649	2181	2439	2202
Events, n	213	117	126	131	112
Median svg/day	0	0.07	0.43	1.00	2.50
HR (95%CI)^*	1 (ref)	1.11 (0.89, 1.39)	0.81 (0.64, 1.03)	0.86 (0.68, 1.09)	0.74 (0.57, 0.96)	0.005
HR (95%CI)^**	1 (ref)	1.26 (1.00, 1.58)	1.01 (0.79, 1.28)	1.04 (0.81, 1.33)	0.91 (0.68, 1.21)	0.13
Fish & Seafood
n	2076	3227	1795	2092	2411
Events, n	112	203	108	131	145
Median svg/day	0	0.14	0.21	0.28	0.57
HR (95%CI)^*	1 (ref)	1.06 (0.84, 1.33)	0.90 (0.70, 1.16)	0.92 (0.72, 1.17)	0.91 (0.71, 1.15)	0.27
HR (95%CI)^**	1 (ref)	1.08 (0.86, 1.36)	0.97 (0.75, 1.26)	0.98 (0.76, 1.26)	0.95 (0.73, 1.24)	0.46
Eggs
n	2077	2127	2885	3189	1322
Events, n	121	92	169	218	99
Median svg/day	0	0.07	0.14	0.43	1.00
HR (95%CI)^*	1 (ref)	0.81 (0.62, 1.07)	1.09 (0.86, 1.37)	1.15 (0.90, 1.47)	1.23 (0.97, 1.56)	0.01
HR (95%CI)^**	1 (ref)	0.79 (0.60, 1.04)	1.05 (0.83, 1.33)	1.03 (0.80, 1.32)	1.08 (0.84, 1.39)	0.19
Nuts & Peanut Butter
n	1951	2842	2363	2183	2262
Events, n	130	155	138	141	135
Median svg/day	0	0.07	0.21	0.43	1.00
HR (95%CI)^*	1 (ref)	0.79 (0.63, 1.01)	0.93 (0.73, 1.19)	0.92 (0.72, 1.17)	0.86 (0.67, 1.11)	0.74
HR (95%CI)^**	1 (ref)	0.83 (0.65, 1.05)	1.03 (0.81, 1.32)	1.04 (0.81, 1.33)	1.00 (0.77, 1.31)	0.42
Legumes
n	2767	2771	828	2853	2382
Events, n	131	164	47	189	168
Median svg/day	0.07	0.14	0.21	0.28	0.57
HR (95%CI)^*	1 (ref)	1.05 (0.82, 1.34)	1.14 (0.88, 1.47)	1.08 (0.84, 1.39)	1.15 (0.90, 1.49)	0.42
HR (95%CI)^**	1 (ref)	1.07 (0.84, 1.37)	1.16 (0.89, 1.51)	1.18 (0.91, 1.53)	1.29 (0.98, 1.70)	0.10

adjusted for age, sex, race, study center, and total energy intake

^**

adjusted for age, sex, race, study center, total energy intake, smoking, cigarette years, education, systolic blood pressure, use of antihypertensive medication, HDLc, total cholesterol, use of lipid lowering medication, body mass index, waist-to-hip ratio, alcohol intake, sports-related physical activity, leisure-related physical activity, carbohydrate intake, fiber intake, fat intake and magnesium intake