Figure 1.
Regional distribution of nonsynonymous mutations in ten ccRCC tumors. Mutations that failed validation were not included. Heat maps indicate the presence of a mutation (yellow) or its absence (blue) in each region. Category 1 high-confidence driver mutations and category 2 probable driver mutations are highlighted in magenta. The table shows the number of nonsynonymous mutations and the ratio of heterogeneous mutations per tumor. An asterisk indicates where VHL methylation was included in the analysis.