Table 3.
Clinical outcomes of cohort studies & protocol type.
| Nr. | Study | Deterioration | No improvement | Improvement No remission | CR | ER/HR | Protocol type |
|---|---|---|---|---|---|---|---|
| 1 | Vermeire et al. (2012).27 (n=4) | - | 4 | - | - | - | NR |
| 2 | Kunde et al. (2013).23 (n=9) | 3g | 3d | 3 | NR | Fresh | |
| 3 | Kump et al. (2013).22 (n=6) | 1b | 3 | 2e | - | - | Frozen |
| 4 | Angelberger et al. (2013).20 (n=5) | 2c | 2 | 1f | - | - | Fresh |
| 5 | Suskind et al. (2014).25 (n=9) | - | - | 1 | 8 | NR | NR |
| 6 | Landy et al. (2013).24 (n=5) | NR | NR | NR | - | - | Fresh |
| 7 | Zhang et al. (2013).28 (n=16) | - | 1 | 3 | 12 | NR | Fresh |
| 8 | Damman et al.(2014).21 (n=7) | 1 | 4 | - | 2 | 1 | Fresh |
| 9 | Vaughn et al. (2014).26 (n=9) | - | 3 | 2 | 4 | - | Frozen |
CR= Clinical remission; ER/HR =Endoscopic or Histologic Remission; NR=Not (exactly) Reported; PUCAI=Pediatric Ulcerative Colitis Activity Index; MCID=Minimal Clinically Important Difference
b
(initial improve then relapse+ colectomy)
c
partial deterioration after 4 wks w/ returning to baseline
d
Improvement >20 PUCAI MCID
e
Additional reduction of (3and 4 pts of mayo score)
f
Reduction by 4 points on Mayo score
g
within PUCAI <20 MCID.