Table 4.
Selection of inflammation and immune response related genes regulated in dyslipidemic subjects after supplementation with fish oil for twelve weeks
| Gene name | Gene symbol | Entrez_ID | Ratio t12: t0 |
|---|---|---|---|
|
Pro-inflammatory genes | |||
| Nitric oxide synthase, inducible |
NOS2 |
4843 |
-4.77 |
| C-C chemokine receptor type 3 |
CCR3 |
1232 |
-4.49 |
| Tumour necrosis factor receptor superfamily member 18 Precursor |
TNFRSF18 |
8784 |
-2.07 |
| Interleukin-31 receptor A Precursor |
IL31RA |
133396 |
-4.74 |
| 72 kDa type IV collagenase Precursor |
MMP2 |
4313 |
-6.16 |
| Interleukin-8 Precursor |
IL8 |
3576 |
-5.67 |
| Tumour necrosis factor receptor superfamily member 5 Precursor |
CD40 |
958 |
-4.72 |
| Interleukin-2 receptor subunit beta Precursor |
IL2RB |
3560 |
-3.22 |
| Interleukin-3 receptor subunit alpha Precursor |
IL3RA |
3563 |
-2.22 |
| Stromelysin-1 Precursor |
MMP3 |
4314 |
-2.17 |
| C-C motif chemokine 5 Precursor |
CCL5 |
6352 |
2.24 |
| CD97 antigen Precursor |
CD97 |
976 |
2.26 |
| Prostaglandin D2 receptor |
PTGDR |
5729 |
4.47 |
| Integrin alpha-L Precursor |
ITGAL |
3683 |
5.07 |
| Arachidonate 5-lipoxygenase-activating protein (FLAP) |
ALOX5AP |
241 |
6.97 |
|
Anti-inflammatory genes | |||
| C-X-C motif chemokine 11 Precursor |
CXCL11 |
6373 |
-2.98 |
| NF-kappa-B-repressing factor |
NKRF |
55922 |
-82.11 |
| NF-kappa-B inhibitor-like protein 2 |
NFKBIL2 |
4796 |
-3.30 |
| Cytokine receptor-like factor 1 Precursor |
CRLF1 |
9244 |
-3.07 |
| Lipopolysaccharide-induced tumour necrosis factor-alpha factor |
LITAF |
9516 |
3.06 |
| Interferon regulatory factor 1 |
IRF1 |
3659 |
3.16 |
| Interferon-alpha/beta receptor alpha chain Precursor |
IFNAR1 |
3454 |
5.13 |
| Suppressor of cytokine signalling 6 |
SOCS6 |
9306 |
6.01 |
|
Immune response related genes | |||
| Suppressor of cytokine signalling 2 |
SOCS2 |
8835 |
-6.05 |
| Disintegrin and metalloproteinase domain-containing protein 10 Precursor |
ADAM10 |
102 |
-5.23 |
| A disintegrin and metalloproteinase with thrombospondin motifs 10 Precursor |
ADAMTS10 |
81794 |
-3.14 |
| Nitric oxide synthase, endothelial |
NOS3 |
4846 |
-2.55 |
| SL cytokine Precursor |
FLT3LG |
2323 |
-2.46 |
| Prostaglandin E2 receptor EP3 subtype |
PTGER3 |
5733 |
-2.21 |
| CD99 antigen-like protein 2 Precursor |
CD99L2 |
83692 |
2.18 |
| Cytokine receptor common gamma chain Precursor |
IL2RG |
3561 |
2.85 |
| Monocyte differentiation antigen CD14 Precursor |
CD14 |
929 |
2.88 |
| Chemokine-like factor (C32) |
CKLF |
51192 |
11.73 |
| T-cell surface glycoprotein CD3 delta chain Precursor |
CD3D |
915 |
7.65 |
| Tumour necrosis factor receptor superfamily member 1B Precursor |
TNFRSF1B |
7133 |
2.51 |
| B-lymphocyte antigen CD20 |
MS4A1 |
931 |
2.12 |
| Interleukin-31 receptor A Precursor |
IL31RA |
133396 |
5.72 |
| Intercellular adhesion molecule 3 Precursor |
ICAM3 |
3385 |
5.85 |
| CD320 antigen Precursor |
CD320 |
51293 |
8.17 |
| CD2 antigen cytoplasmic tail-binding protein 2 |
CD2BP2 |
10421 |
8.77 |
| T-cell antigen CD7 Precursor |
CD7 |
924 |
2.30 |
| C-C chemokine receptor-like 2 (Putative MCP-1 chemokine receptor) | CCRL2 | 9034 | 17.55 |