Table 3.
Mutations in the M1, M2, NS1, and NS2 genes for clones of mouse-adapted A/HK/1/68
| Virus | Amino acid variation (nucleotide position)
|
|||||
|---|---|---|---|---|---|---|
| M1
|
M2
|
NS1
|
NS2
|
|||
| 167 (524) | 232 (617) | 44 (155) | 23 (94) | 103 (333) | 88 (289) | |
| HK | Thr (A) | Asp (G) | Asp (G) | Val (T) | Phe (T) | Lys (A) |
| HKMA12 | − | − | − | − | − | − |
| HKMA12A | − | − | − | − | − | − |
| HKMA12B | − | − | − | − | − | − |
| HKMA20 | − | Asn (A) | − | Ala (C) | − | − |
| HKMA20A | − | Asn (A) | − | Ala (C) | − | − |
| HKMA20B | − | − | Asn (A) | − | Leu (C) | Arg (G) |
| HKMA20C | Ala (G) | − | Asn (A) | − | Leu (C) | − |
| HKMA20D | − | − | − | − | Leu (C) | − |
| HKMA20E | − | − | Asn (A) | − | − | − |
−, indicates wild-type sequence.