Figure 5. Western blot testing shows the expression of hyperphosphorylated Tau induced by transient cerebral ischemia/reperfusion.
The level of Tau protein increased in the ischemic cortex of the transient cerebral ischemia/reperfusion subgroup compared to the corresponding region in the sham group (A through D). The levels of AT8 and Tau-5 increased obviously at 1 w after transient cerebral ischemia/reperfusion (B and D), whereas a similar increase was detected in the level of P-tau only at 6 h after transient cerebral ischemia/reperfusion (C). The asterisk indicates a significant difference (P<0.05) between this subgroup and the other five subgroup.